Description

Palbociclib 100 mg (Paleno) – Targeted Treatment for Certain Breast Cancers

Palbociclib 100 mg (Paleno) is a prescription anticancer medicine containing Palbociclib 100mg, a targeted therapy belonging to the CDK4/6 inhibitor class. It works by blocking cyclin-dependent kinases 4 and 6 (CDK4/6), which can slow the growth and division of cancer cells.

Palbociclib is used in combination with hormonal therapy for certain types of HR-positive, HER2-negative advanced or metastatic breast cancer. It may be prescribed with an aromatase inhibitor or with fulvestrant, depending on the patient’s treatment history and clinical condition. Treatment should be supervised by a qualified oncologist.

• Key Features

1. Contains Palbociclib 100mg per capsule/tablet
2. Prescription-only targeted anticancer medicine
3. Belongs to the CDK4/6 inhibitor class
4. Used for certain HR-positive, HER2-negative breast cancers
5. Commonly used in combination with hormonal therapy
6. Oral medicine for convenient administration

How to Take Palbociclib 100 mg

Take Palbociclib exactly as prescribed by your oncologist. Swallow the medicine whole with a glass of water. Do not crush, chew, or open the capsule unless specifically instructed.

Palbociclib is generally taken once daily for 21 consecutive days, followed by 7 days without treatment, forming a 28-day cycle. It should be taken at approximately the same time each day.

Depending on the formulation, Palbociclib may be taken with or without food. Follow the instructions provided with your specific product.

Avoid grapefruit and grapefruit juice, as they may increase Palbociclib levels in the body.

• General Dosage Reference

Treatment	Recommended Adult Dose
HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer	125mg once daily for 21 days followed by 7 days off, or as prescribed
Dose Reduction	100mg once daily when medically indicated
Further Dose Reduction	75mg once daily when required

Palbociclib 100 mg is commonly a dose-reduction strength. The appropriate dose and treatment schedule should always be determined by the treating oncologist based on blood counts, liver function, side effects, and individual treatment response.

Safety Information

Before starting Palbociclib 100 mg, inform your healthcare provider if you have liver disease, infections, or a history of low blood cell counts.

Palbociclib can reduce blood-cell counts, particularly neutrophils, which may increase the risk of infection. Your doctor will regularly monitor blood counts during treatment.

Tell your oncologist about all prescription medicines, over-the-counter medicines, vitamins, and herbal supplements because Palbociclib can interact with several medicines.

Common side effects may include low white blood cell counts, infections, tiredness, nausea, mouth sores, hair thinning, diarrhea, and decreased appetite.

Seek immediate medical attention if you develop fever, chills, difficulty breathing, severe weakness, unusual bleeding, or other signs of serious infection.

Product Specifications

Specification	Information
Brand	Paleno
Generic Name	Palbociclib
Active Ingredient	Palbociclib
Strength	100mg
Dosage Form	Oral Capsule/Tablet*
Drug Class	CDK4/6 Inhibitor
Route of Administration	Oral
Primary Use	HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer
Prescription Status	Prescription Required
Storage	Store according to the manufacturer’s labeled instructions

Dosage form may vary according to the specific manufacturer/product.

Frequently Asked Questions

What is Palbociclib 100 mg used for?
Palbociclib 100 mg is used with hormonal therapy for certain HR-positive, HER2-negative advanced or metastatic breast cancers.

How does Palbociclib work?
It blocks CDK4 and CDK6 enzymes, helping slow the progression and division of certain cancer cells.

How is Palbociclib 100 mg usually taken?
Palbociclib is commonly taken once daily for 21 days followed by 7 days off, but the exact dose and schedule must be determined by the oncologist.

What are the common side effects?
Common side effects include low blood cell counts, infections, tiredness, nausea, mouth sores, hair thinning, and diarrhea.

Does Palbociclib require blood tests?
Yes. Regular blood-count monitoring is important during treatment because Palbociclib can reduce white blood cells and other blood-cell counts.