Description

Instgra 50 mg (Dolutegravir) – Prescription Antiretroviral Medicine for HIV-1 Treatment

Instgra 50 mg is a prescription antiretroviral medicine formulated with Dolutegravir 50 mg, an active ingredient widely used as part of combination antiretroviral therapy for the treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection in adults and eligible adolescents. Dolutegravir belongs to the Integrase Strand Transfer Inhibitor (INSTI) class of medicines. It works by blocking the HIV integrase enzyme, preventing the virus from integrating its genetic material into human immune cells and thereby reducing viral replication.

Instgra 50 mg helps lower the amount of HIV in the body, supports immune system function, and reduces the risk of HIV-related complications when taken consistently as prescribed. The medicine does not cure HIV infection and should always be used in combination with other antiretroviral medicines recommended by a qualified healthcare professional.

The medicine is prescribed only after proper medical evaluation, as the appropriate dose depends on the patient’s treatment history, viral resistance profile, kidney and liver function, and overall health condition.

• Key Features

1. Contains Dolutegravir 50 mg per tablet
2. Prescription-only antiretroviral medication
3. Oral tablet for convenient administration
4. Integrase Strand Transfer Inhibitor (INSTI)
5. Used as part of combination therapy for HIV-1 infection
6. Helps suppress HIV viral replication
7. Manufactured under quality pharmaceutical standards

How to Take Instgra 50 mg

For the best therapeutic effect, take Instgra 50 mg exactly as directed by your healthcare provider. It is generally taken once daily, with or without food. Some patients with certain drug-resistant HIV strains or when taking interacting medicines may require 50 mg twice daily, as determined by their physician.

Swallow the tablet whole with a glass of water. Do not crush, chew, or split the tablet unless advised by your healthcare provider. Take the medicine at the same time every day and avoid missing doses to maintain effective viral suppression.

If taking calcium or iron supplements, antacids, or multivitamins containing minerals, follow your healthcare provider’s instructions regarding the timing of these products, as they may reduce Dolutegravir absorption.

• General Dosage Reference

Medical Condition	Recommended Adult Dose
HIV-1 Infection	50 mg once daily as part of combination therapy
Certain Drug-Resistant HIV or Drug Interactions	50 mg twice daily as directed by the physician
Pediatric Patients	Dose determined according to body weight
Other HIV Treatment Regimens	As directed by the treating physician

The exact dosage should always be determined by your healthcare provider based on treatment history, viral resistance profile, concomitant medications, and current HIV treatment guidelines.

Safety Information

Before starting Instgra 50 mg, tell your healthcare provider if you have liver disease, hepatitis B or hepatitis C infection, kidney disease, or any known allergy to Dolutegravir. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using this medicine.

Inform your physician about all prescription medicines, over-the-counter drugs, vitamins, herbal supplements, and antacids, as some medicines may interact with Dolutegravir and require dose adjustments or special timing.

Most people tolerate Instgra 50 mg well when taken as prescribed. However, some individuals may experience mild side effects such as headache, insomnia, nausea, diarrhea, dizziness, or fatigue. Serious side effects may include severe allergic reactions, liver problems, depression or mood changes in susceptible individuals, and severe skin reactions. Seek immediate medical attention if you experience swelling of the face or throat, difficulty breathing, yellowing of the skin or eyes, severe rash, or persistent mood changes.

Regular monitoring of treatment response and liver function may be recommended during therapy.

Product Specifications

Specification	Information
Brand	Instgra
Generic Name	Dolutegravir
Active Ingredient	Dolutegravir
Strength	50 mg
Dosage Form	Oral Tablet
Drug Class	Integrase Strand Transfer Inhibitor (INSTI)
Route of Administration	Oral
Prescription Status	Prescription Required
Storage	Store below 30°C in a cool, dry place away from moisture and direct sunlight

Frequently Asked Questions

Can Instgra 50 mg be taken with food?

Yes. Instgra 50 mg may generally be taken with or without food unless your healthcare provider advises otherwise.

Is Instgra 50 mg a cure for HIV?

No. Instgra 50 mg does not cure HIV infection. It helps control viral replication when used as part of a complete antiretroviral treatment regimen.

Can Instgra 50 mg be used alone?

No. Instgra 50 mg should always be used in combination with other prescribed antiretroviral medicines as recommended by your healthcare provider.

Can I take antacids with Instgra 50 mg?

Antacids, calcium supplements, iron supplements, and certain multivitamins may interfere with Dolutegravir absorption. Follow your healthcare provider’s instructions regarding the timing of these products.

What should I do if I miss a dose?

Take the missed dose as soon as you remember if it is not close to your next scheduled dose. Do not take two doses together. Consult your healthcare provider if you are unsure.