Description

Combutol 400 (Ethambutol) – Effective Treatment for Tuberculosis (TB)

Combutol 400 is a prescription anti-tuberculosis medicine formulated with Ethambutol 400mg, an active ingredient used in combination with other anti-TB medications for the treatment of active tuberculosis (TB). Ethambutol works by inhibiting the growth of Mycobacterium tuberculosis, preventing the bacteria from multiplying and helping eliminate the infection when used as part of a complete treatment regimen.

Combutol 400 is commonly prescribed alongside other first-line anti-tuberculosis medicines such as isoniazid, rifampicin, and pyrazinamide. Because tuberculosis treatment varies depending on the patient’s body weight, infection severity, kidney function, and treatment response, this medicine should only be used under the supervision of a qualified healthcare professional.

• Key Features

1. Contains Ethambutol 400mg per tablet
2. Prescription-only anti-tuberculosis medication
3. Oral tablet for convenient administration
4. Used as part of combination therapy for active tuberculosis
5. Helps reduce the risk of drug-resistant tuberculosis
6. Manufactured under quality pharmaceutical standards

How to Take Combutol 400

For the best therapeutic effect, take Combutol 400 exactly as directed by your healthcare provider. Swallow the tablet whole with a glass of water. It may be taken with or without food, although taking it after meals may help reduce stomach discomfort if recommended by your doctor.

Do not crush, chew, or split the tablet unless instructed by your physician. Avoid skipping doses or stopping treatment early, as incomplete tuberculosis treatment may lead to treatment failure and drug resistance.

• General Dosage Reference

Medical Condition	Recommended Adult Dose
Active Tuberculosis	15–25 mg/kg orally once daily as part of combination therapy
Initial Treatment Phase	As prescribed by the treating physician
Drug-Resistant Tuberculosis	Dose determined by TB specialist
Patients with Kidney Impairment	Dose adjustment may be required
Other Uses	As directed by the treating physician

The exact dosage should always be determined by your healthcare provider based on body weight, kidney function, infection severity, and treatment regimen.

Safety Information

Before taking Combutol 400, inform your healthcare provider if you have kidney disease, liver disease, optic neuritis, vision problems, gout, or any allergy to ethambutol.

Ethambutol may affect eyesight, including blurred vision, reduced visual acuity, or difficulty distinguishing red and green colors. Regular eye examinations are recommended before and during treatment, particularly during prolonged therapy.

Women who are pregnant, planning pregnancy, or breastfeeding should consult their healthcare provider before using this medicine. Inform your physician about all prescription medicines, over-the-counter drugs, vitamins, and herbal supplements to minimize the risk of potential drug interactions.

Most people tolerate Combutol 400 well when taken as prescribed. However, some individuals may experience mild side effects such as nausea, vomiting, stomach discomfort, headache, dizziness, joint pain, skin rash, or loss of appetite. Seek immediate medical attention if you experience severe allergic reactions, persistent vision changes, numbness or tingling, or unusual weakness.

Product Specifications

Specification	Information
Brand	Combutol 400
Generic Name	Ethambutol
Active Ingredient	Ethambutol Hydrochloride
Strength	400mg
Dosage Form	Oral Tablet
Drug Class	Antitubercular Agent
Route of Administration	Oral
Prescription Status	Prescription Required
Storage	Store below 25°C in a cool, dry place away from moisture and direct sunlight

Frequently Asked Questions

Can Combutol 400 be taken with food?

Yes. It may be taken with or without food. If stomach upset occurs, taking it with food may improve tolerability.

How quickly does Combutol 400 start working?

The medicine begins working after absorption, but improvement in tuberculosis symptoms generally occurs gradually over several weeks as part of combination therapy.

Can Combutol 400 be used alone to treat tuberculosis?

No. Ethambutol should always be used together with other anti-tuberculosis medicines to prevent drug resistance and ensure effective treatment.

Can I purchase Combutol 400 online?

Availability depends on your country’s regulations. A valid prescription may be required before purchase.

What should I do if I miss a dose?

Take the missed dose as soon as you remember unless it is almost time for your next scheduled dose. Do not take two doses together. Consult your healthcare provider if you are unsure how to proceed.